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Cervical Screening with the ThinPrep® Pap test

NEWS: Liquid Based Cytology (LBC), such as the ThinPrep Pap test, is now listed on the Medicare Benefits Scheme (MBS) – Item 73069. This is an interim arrangement by the Department of Health until the renewed National Cervical Screening Program is implemented.

From 1 May - 30 November 2017:

LBC will be added to the MBS. For each patient a Medicare rebate will only be payable for one cervical screening test for cytology, either the LBC test or the conventional cytology test. If you choose to do both tests, you will need to inform patients that they will incur an out-of-pocket cost.

The LBC test will be set at a Medicare fee of $36.00 per test and will exist alongside the rebate for the conventional cytology test.

Please refer to the Department of Health’s letter here for the full details.


The ThinPrep® Pap Test (Liquid Based Cytology)

The ThinPrep Pap Test is a liquid-based Cervical Screening Test that employs an alcohol based fluid transport medium to immediately preserve cells, allow for out of vial Human Papillomavirus testing, and allows for the automated slide processing which eliminates debris and distributes a representative portion of cells on a slide in a thin, even layer when required. A ThinPrep Pap test slide is clearer and easier to read as it minimises obscuring blood and mucous, to provide increased accuracy for assessment of the cells. The ThinPrep process ultimately improves the quality of the sample, preparing a slide that is clearer for diagnostic review.*

The ThinPrep Pap test sample is the complete solution with multiple testing options performed from one vial: Human Papillomavirus (HPV), Liquid Based Cytology, and also chlamydia and gonorrhoea, Trichomonas vaginalis and Mycoplasma genitalium.1

Proven effectiveness

Research shows the ThinPrep Pap test as more likely to detect high-grade abnormalities compared to the conventional pap smear.*5,6 In Australia, the ThinPrep system is clinically proven to be 27% more effective at detecting high-grade abnormalities and 56% more effective at finding low-grade abnormalities compared to the conventional Pap smear.5,6 In addition there is a 94% decrease in unsatisfactory reports with the ThinPrep Pap test.7

Reproducible, representative sample

With the ThinPrep Pap test, the clinician collects the Cervical Screening Test sample using either a broom-like device or the brush/spatula combination. Instead of smearing a portion of the sample onto a slide, the collection device is rinsed in the ThinPrep vial, capturing virtually the entire cell sample. The specimen is then sent to the laboratory, where an HPV test is performed, and when required an automated processor prepares a slide by dispersing and filtering the sample and then placing a representative sample on the slide.

Improved slide quality

In addition to the ThinPrep Pap test’s improved slide quality, Hologic’s proprietary technology eliminates common errors associated with preparing a specimen.*


The Complete Solution

One vial, multiple testing options. From a single specimen collected in the ThinPrep Pap test vial, doctors can screen for cervical disease and HPV, as well as common sexually transmitted infections (STIs) confidently and accurately.*

  • Cytology
  • Human papillomavirus
  • Chlamydia/Gonorrhoea
  • Trichomonas vaginalis
  • Mycoplasma genitalium

Note: Molecular tests, such as Human papillomavirus, chlamydia, gonorrhoea, Trichomonas vaginalis, Mycoplasma genitalium, can be performed from the same material collected for the ThinPrep Pap Test.

Contact your laboratory for more information.

Correct Collection Counts

An optimal ThinPrep Cervical Screening Test specimen relies on accurate cell collection.

One of the best ways to achieve this is to avoid the use of lubricants as they may interfere with pathology tests. However, if necessary, a small amount of water-soluable, carbomer-free lubricant is best, applied sparingly to the outer portion of the speculum only, avoiding the tip.

The sampling protocols below provide a step-by-step guide to assist in adequate cell collection and to assist in gaining a clear read, first time, every time.

ThinPrep® Pap Test

  1. Data on file with Hologic, Inc.
  2. Davey E, et al. Accuracy of reading liquid based cytology slides using the ThinPrep Imager compared with conventional cytology: prospective study. British Medical Journal. 2007;335(7609):28
  3. ThinPrep 2000 System Package Insert 2011
  4. United States Food & Drug Administration (FDA)
  5. Roberts J.M. A Three-Armed Trial of the ThinPrep Imaging System. Diagnostic Cytopathology, vol. 35, no. 2, 96-102, 20
  6. Hutchinson M.L. Homogenous Sampling Accounts for the Increased Diagnostic Accuracy Using the ThinPrep Processor Am J Clin Path. 101:215-219, 1994References: